High-resolution quantitative profiling of tRNA abundance and modification status in eukaryotes by mim-tRNAseq

Measurements of cellular tRNA abundance are hampered by pervasive blocks to cDNA synthesis at modified nucleosides and the extensive similarity among tRNA genes. We overcome these limitations with modification-induced misincorporation tRNA sequencing (mim-tRNAseq), which combines a workflow for full...

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Detalles Bibliográficos
Autores principales: Behrens, Andrew, Rodschinka, Geraldine, Nedialkova, Danny D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062790/
https://www.ncbi.nlm.nih.gov/pubmed/33581077
http://dx.doi.org/10.1016/j.molcel.2021.01.028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062790/
https://www.ncbi.nlm.nih.gov/pubmed/33581077
http://dx.doi.org/10.1016/j.molcel.2021.01.028

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