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A Systematic Screening of Traditional Chinese Medicine Identifies Two Novel Inhibitors Against the Cytotoxic Aggregation of Amyloid Beta

The toxic aggregates of amyloid beta (Aβ) disrupt the cell membrane, induce oxidative stress and mitochondrial dysfunction, and eventually lead to Alzheimer’s disease (AD). Intervening with this cytotoxic aggregation process has been suggested as a potential therapeutic approach for AD and other pro...

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Detalles Bibliográficos
Autores principales: Ma, Liang, Zheng, Jiaojiao, Chen, Huijing, Zeng, Xia, Wang, Shilin, Yang, Chen, Li, Xi, Xiao, Yushuo, Zheng, Ling, Chen, Hong, Huang, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062920/
https://www.ncbi.nlm.nih.gov/pubmed/33897425
http://dx.doi.org/10.3389/fphar.2021.637766