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Association analysis of miRNA-related genetic polymorphisms in miR-143/145 and KRAS with colorectal cancer susceptibility and survival

Background: There is accumulating evidence of aberrant expression of miR-143 and miR-145 and their target gene KRAS in colorectal cancer (CRC). We hypothesize that single nucleotide polymorphisms (SNPs) within or near mRNA–microRNA (miRNA) binding sites may affect miRNA/target gene interaction, resu...

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Detalles Bibliográficos
Autores principales: Wang, Danyang, Liu, Qingmin, Ren, Yanjun, Zhang, Yan, Wang, Xin, Liu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062955/
https://www.ncbi.nlm.nih.gov/pubmed/33825830
http://dx.doi.org/10.1042/BSR20204136