Tetra-arylborate lipophilic anions as targeting groups

Tetraphenylborate (TPB) anions traverse membranes but are excluded from mitochondria by the membrane potential (Δψ). TPB-conjugates also distributed across membranes in response to Δψ, but surprisingly, they rapidly entered cells. They accumulated within lysosomes following endocystosis. This pH-ind...

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Detalles Bibliográficos
Autores principales: Gaddale Devanna, Kishore K., Gawel, Justyna M., Prime, Tracy A., Cvetko, Filip, Benincá, Cristiane, Caldwell, Stuart T., Negoda, Alexander, Harrison, Andrew, James, Andrew M., Pavlov, Evgeny V., Murphy, Michael P., Hartley, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062962/
https://www.ncbi.nlm.nih.gov/pubmed/33634803
http://dx.doi.org/10.1039/d0cc07924c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062962/
https://www.ncbi.nlm.nih.gov/pubmed/33634803
http://dx.doi.org/10.1039/d0cc07924c

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