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Temperature Based Process Characterization of Pharmaceutical Freeze-Thaw Operations
In biopharmaceutical production processes, freeze-thaw operations are used to ensure product integrity during long hold times, but they also introduce additional stresses such as freeze concentration gradients that might lead to a loss of protein activity. Process characterization of freeze-thaw ope...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062970/ https://www.ncbi.nlm.nih.gov/pubmed/33898399 http://dx.doi.org/10.3389/fbioe.2021.617770 |