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Genome-Wide Association Study of Non-syndromic Orofacial Clefts in a Multiethnic Sample of Families and Controls Identifies Novel Regions

Orofacial clefts (OFCs) are among the most prevalent craniofacial birth defects worldwide and create a significant public health burden. The majority of OFCs are non-syndromic and vary in prevalence by ethnicity. Africans have the lowest prevalence of OFCs (~ 1/2,500), Asians have the highest preval...

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Detalles Bibliográficos
Autores principales: Mukhopadhyay, Nandita, Feingold, Eleanor, Moreno-Uribe, Lina, Wehby, George, Valencia-Ramirez, Luz Consuelo, Muñeton, Claudia P. Restrepo, Padilla, Carmencita, Deleyiannis, Frederic, Christensen, Kaare, Poletta, Fernando A., Orioli, Ieda M., Hecht, Jacqueline T., Buxó, Carmen J., Butali, Azeez, Adeyemo, Wasiu L., Vieira, Alexandre R., Shaffer, John R., Murray, Jeffrey C., Weinberg, Seth M., Leslie, Elizabeth J., Marazita, Mary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062975/
https://www.ncbi.nlm.nih.gov/pubmed/33898419
http://dx.doi.org/10.3389/fcell.2021.621482