G6PD Polymorphisms and Hemolysis After Antimalarial Treatment With Low Single-Dose Primaquine: A Pooled Analysis of Six African Clinical Trials

Primaquine (PQ) is an antimalarial drug with the potential to reduce malaria transmission due to its capacity to clear mature Plasmodium falciparum gametocytes in the human host. However, the large-scale roll-out of PQ has to be counterbalanced by the additional risk of drug-induced hemolysis in ind...

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Detalles Bibliográficos
Autores principales: Sepúlveda, Nuno, Grignard, Lynn, Curry, Jonathan, Mahey, Laleta, Bastiaens, Guido J. H., Tiono, Alfred B., Okebe, Joseph, Coulibaly, Sam A., Gonçalves, Bronner P., Affara, Muna, Ouédraogo, Alphonse, Bougouma, Edith C., Sanou, Guillaume S., Nébié, Issa, Lanke, Kjerstin, Sirima, Sodiomon B., Dicko, Alassane, d’Alessandro, Umberto, Clark, Taane G., Campino, Susana, Chen, Ingrid, Eziefula, Alice C., Gosling, Roly, Bousema, Teun, Drakeley, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062977/
https://www.ncbi.nlm.nih.gov/pubmed/33897764
http://dx.doi.org/10.3389/fgene.2021.645688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062977/
https://www.ncbi.nlm.nih.gov/pubmed/33897764
http://dx.doi.org/10.3389/fgene.2021.645688

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