Proteomic Profiling of IgG1 Producing CHO Cells Using LC/LC-SPS-MS(3): The Effects of Bioprocessing Conditions on Productivity and Product Quality

The biopharmaceutical market is dominated by monoclonal antibodies, the majority of which are produced in Chinese hamster ovary (CHO) cell lines. Intense cell engineering, in combination with optimization of various process parameters results in increasing product titers. To enable further improveme...

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Detalles Bibliográficos
Autores principales: Strasser, Lisa, Farrell, Amy, Ho, Jenny T. C., Scheffler, Kai, Cook, Ken, Pankert, Patrick, Mowlds, Peter, Viner, Rosa, Karger, Barry L., Bones, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062983/
https://www.ncbi.nlm.nih.gov/pubmed/33898396
http://dx.doi.org/10.3389/fbioe.2021.569045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062983/
https://www.ncbi.nlm.nih.gov/pubmed/33898396
http://dx.doi.org/10.3389/fbioe.2021.569045

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