MicroRNA governs bistable cell differentiation and lineage segregation via a noncanonical feedback

Positive feedback driven by transcriptional regulation has long been considered a key mechanism underlying cell lineage segregation during embryogenesis. Using the developing spinal cord as a paradigm, we found that canonical, transcription‐driven feedback cannot explain robust lineage segregation o...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chung‐Jung, Liau, Ee Shan, Lee, Yi‐Han, Huang, Yang‐Zhe, Liu, Ziyi, Willems, Andrew, Garside, Victoria, McGlinn, Edwina, Chen, Jun‐An, Hong, Tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062999/
https://www.ncbi.nlm.nih.gov/pubmed/33890404
http://dx.doi.org/10.15252/msb.20209945

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8062999/
https://www.ncbi.nlm.nih.gov/pubmed/33890404
http://dx.doi.org/10.15252/msb.20209945

Ejemplares similares