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A Mini Review on Capillary Isoelectric Focusing-Mass Spectrometry for Top-Down Proteomics

Mass spectrometry (MS)-based top-down proteomics (TDP) requires high-resolution separation of proteoforms before electrospray ionization (ESI)-MS and tandem mass spectrometry (MS/MS). Capillary isoelectric focusing (cIEF)-ESI-MS and MS/MS could be an ideal method for TDP because cIEF can enable sepa...

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Detalles Bibliográficos
Autores principales: Xu, Tian, Sun, Liangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063032/
https://www.ncbi.nlm.nih.gov/pubmed/33898392
http://dx.doi.org/10.3389/fchem.2021.651757