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A Mini Review on Capillary Isoelectric Focusing-Mass Spectrometry for Top-Down Proteomics
Mass spectrometry (MS)-based top-down proteomics (TDP) requires high-resolution separation of proteoforms before electrospray ionization (ESI)-MS and tandem mass spectrometry (MS/MS). Capillary isoelectric focusing (cIEF)-ESI-MS and MS/MS could be an ideal method for TDP because cIEF can enable sepa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063032/ https://www.ncbi.nlm.nih.gov/pubmed/33898392 http://dx.doi.org/10.3389/fchem.2021.651757 |