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Sirt2 in the Spinal Cord Regulates Chronic Neuropathic Pain Through Nrf2-Mediated Oxidative Stress Pathway in Rats

Reduction in Nrf2-mediated antioxidant response in the central nervous system plays an important role in the development and maintenance of neuropathic pain (NP). However, the mechanisms regulating Nrf2 activity in NP remain unclear. A recent in vitro study revealed that Sirt2, a member of the sirtu...

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Detalles Bibliográficos
Autores principales: Zhao, Mengnan, Zhang, Xiaojiao, Tao, Xueshu, Zhang, Bohan, Sun, Cong, Wang, Pinying, Song, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063033/
https://www.ncbi.nlm.nih.gov/pubmed/33897435
http://dx.doi.org/10.3389/fphar.2021.646477