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Non-linear Normalization for Non-UMI Single Cell RNA-Seq

Single cell RNA-seq data, like data from other sequencing technology, contain systematic technical noise. Such noise results from a combined effect of unequal efficiencies in the capturing and counting of mRNA molecules, such as extraction/amplification efficiency and sequencing depth. We show that...

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Detalles Bibliográficos
Autores principales:	Wu, Zhijin, Su, Kenong, Wu, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063035/ https://www.ncbi.nlm.nih.gov/pubmed/33897755 http://dx.doi.org/10.3389/fgene.2021.612670

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