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Abnormal Calcium Handling in Duchenne Muscular Dystrophy: Mechanisms and Potential Therapies

Duchenne muscular dystrophy (DMD) is an X-linked muscle-wasting disease caused by the loss of dystrophin. DMD is associated with muscle degeneration, necrosis, inflammation, fatty replacement, and fibrosis, resulting in muscle weakness, respiratory and cardiac failure, and premature death. There is...

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Detalles Bibliográficos
Autores principales: Mareedu, Satvik, Million, Emily D., Duan, Dongsheng, Babu, Gopal J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063049/
https://www.ncbi.nlm.nih.gov/pubmed/33897454
http://dx.doi.org/10.3389/fphys.2021.647010