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MicroRNA-155 Regulates MAIT1 and MAIT17 Cell Differentiation

Mucosal-associated invariant T (MAIT) cells are innate-like T cells that develop in the thymus through three maturation stages to acquire effector function and differentiate into MAIT1 (T-bet(+)) and MAIT17 (RORγt(+)) subsets. Upon activation, MAIT cells release IFN-γ and IL-17, which modulate a bro...

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Detalles Bibliográficos
Autores principales: Liu, Tingting, Wang, Jie, Subedi, Kalpana, Yi, Qijun, Zhou, Li, Mi, Qing-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063056/
https://www.ncbi.nlm.nih.gov/pubmed/33898469
http://dx.doi.org/10.3389/fcell.2021.670531