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Solid-state packing dictates the unexpected solubility of aromatic peptides

The understanding and prediction of the solubility of biomolecules, even of the simplest ones, reflect an open question and unmet need. Short aromatic tripeptides are among the most highly aggregative biomolecules. However, in marked contrast, Ala-Phe-Ala (AFA) was surprisingly found to be non-aggre...

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Detalles Bibliográficos
Autores principales: Bera, Santu, Dong, Xuewei, Krishnarjuna, Bankala, Raab, Shannon A., Hales, David A., Ji, Wei, Tang, Yiming, Shimon, Linda J.W., Ramamoorthy, Ayyalusamy, Clemmer, David E., Wei, Guanghong, Gazit, Ehud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063180/
https://www.ncbi.nlm.nih.gov/pubmed/33928264
http://dx.doi.org/10.1016/j.xcrp.2021.100391