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Solid-state packing dictates the unexpected solubility of aromatic peptides
The understanding and prediction of the solubility of biomolecules, even of the simplest ones, reflect an open question and unmet need. Short aromatic tripeptides are among the most highly aggregative biomolecules. However, in marked contrast, Ala-Phe-Ala (AFA) was surprisingly found to be non-aggre...
Autores principales: | Bera, Santu, Dong, Xuewei, Krishnarjuna, Bankala, Raab, Shannon A., Hales, David A., Ji, Wei, Tang, Yiming, Shimon, Linda J.W., Ramamoorthy, Ayyalusamy, Clemmer, David E., Wei, Guanghong, Gazit, Ehud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063180/ https://www.ncbi.nlm.nih.gov/pubmed/33928264 http://dx.doi.org/10.1016/j.xcrp.2021.100391 |
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