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Effect of Dapagliflozin on Urine Metabolome in Patients with Type 2 Diabetes

CONTEXT: Inhibitors of sodium-glucose cotransporters-2 have cardio- and renoprotective properties. However, the underlying mechanisms remain indeterminate. OBJECTIVE: To evaluate the effect of dapagliflozin on renal metabolism assessed by urine metabolome analysis in patients with type 2 diabetes. D...

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Detalles Bibliográficos
Autores principales: Bletsa, Evdoxia, Filippas-Dekouan, Sebastien, Kostara, Christina, Dafopoulos, Panagiotis, Dimou, Aikaterini, Pappa, Eleni, Chasapi, Styliani, Spyroulias, Georgios, Koutsovasilis, Anastasios, Bairaktari, Eleni, Ferrannini, Ele, Tsimihodimos, Vasilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063232/
https://www.ncbi.nlm.nih.gov/pubmed/33592103
http://dx.doi.org/10.1210/clinem/dgab086