PKM2 regulates proliferation and apoptosis through the Hippo pathway in oral tongue squamous cell carcinoma

Oral tongue squamous cell carcinoma (OTSCC) is a highly malignant type of tumor. The 5-year survival rate of patients with advanced tongue squamous cell carcinoma is only ~50%. Pyruvate kinase M2 (PKM2) is the key rate-limiting enzyme of glycolysis, maintaining the Warburg effect in tumor cells. The...

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Detalles Bibliográficos
Autores principales: Luo, Jia, Zhang, Lei, Guo, Lijuan, Yang, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063272/
https://www.ncbi.nlm.nih.gov/pubmed/33907571
http://dx.doi.org/10.3892/ol.2021.12722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063272/
https://www.ncbi.nlm.nih.gov/pubmed/33907571
http://dx.doi.org/10.3892/ol.2021.12722

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