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DNA hypermethylation contributes to colorectal cancer metastasis by regulating the binding of CEBPB and TFCP2 to the CPEB1 promoter

BACKGROUND: Aberrant DNA methylation has been firmly established as a factor contributing to the pathogenesis of colorectal cancer (CRC) via its capacity to silence tumour suppressor genes. However, the methylation status of multiple tumour suppressor genes and their roles in promoting CRC metastasi...

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Detalles Bibliográficos
Autores principales: Shao, Keke, Pu, Weilin, Zhang, Jianfeng, Guo, Shicheng, Qian, Fei, Glurich, Ingrid, Jin, Qing, Ma, Yanyun, Ju, Shaoqing, Zhang, Zhao, Ding, Weifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063327/
https://www.ncbi.nlm.nih.gov/pubmed/33892791
http://dx.doi.org/10.1186/s13148-021-01071-z