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Identification of ZBTB18 as a novel colorectal tumor suppressor gene through genome-wide promoter hypermethylation analysis

BACKGROUND: Cancer initiation and progression are driven by genetic and epigenetic changes. Although genome/exome sequencing has significantly contributed to the characterization of the genetic driver alterations, further investigation is required to systematically identify cancer driver genes regul...

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Detalles Bibliográficos
Autores principales: Bazzocco, Sarah, Dopeso, Higinio, Martínez-Barriocanal, Águeda, Anguita, Estefanía, Nieto, Rocío, Li, Jing, García-Vidal, Elia, Maggio, Valentina, Rodrigues, Paulo, de Marcondes, Priscila Guimarães, Schwartz, Simo, Aaltonen, Lauri A., Sánchez, Alex, Mariadason, John M., Arango, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063439/
https://www.ncbi.nlm.nih.gov/pubmed/33892786
http://dx.doi.org/10.1186/s13148-021-01070-0