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Pharmacokinetics of five phthalides in volatile oil of Ligusticum sinense Oliv.cv. Chaxiong, and comparison study on physicochemistry and pharmacokinetics after being formulated into solid dispersion and inclusion compound

BACKGROUNDS: The dried rhizome of Ligusticum sinense Oliv.cv. Chaxiong has been used to treat cardiovascular and cerebrovascular diseases, atherosclerosis, anemia and stroke. A high purity extract from chaxiong (VOC, brownish yellow oil) was extracted and separated. Its main components were senkyuno...

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Detalles Bibliográficos
Autores principales: Hu, Peng-yi, Zhong, Ying-huai, Feng, Jian-fang, Li, Dong-xun, Deng, Ping, Zhang, Wen-liu, Lei, Zhi-qiang, Liu, Xue-mei, Zhang, Guo-song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063472/
https://www.ncbi.nlm.nih.gov/pubmed/33888111
http://dx.doi.org/10.1186/s12906-021-03289-z