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Multi-Factor Clustering Incorporating Cell Motility Predicts T Cell Expansion Potential

Expansion of an initial population of T cells is essential for cellular immunotherapy. In Chronic Lymphocytic Leukemia (CLL), expansion is often complicated by lack of T cell proliferation, as these cells frequently show signs of exhaustion. This report seeks to identify specific biomarkers or measu...

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Detalles Bibliográficos
Autores principales: Lee, Joanne H., Shao, Shuai, Kim, Michelle, Fernandes, Stacey M., Brown, Jennifer R., Kam, Lance C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063612/
https://www.ncbi.nlm.nih.gov/pubmed/33898440
http://dx.doi.org/10.3389/fcell.2021.648925