Clonal Evolution of a High-Grade Pediatric Glioma With Distant Metastatic Spread

OBJECTIVE: High-grade glioma (HGG) rarely spreads outside the CNS. To test the hypothesis that the lesions were metastases originating from an HGG, we sequenced the relapsing HGG and distant extraneural lesions. METHODS: We performed whole-exome sequencing of an HGG lesion, its local relapse, and di...

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Detalles Bibliográficos
Autores principales: Marinari, Eliana, Dutoit, Valerie, Nikolaev, Sergey, Vargas, Maria-Isabel, Schaller, Karl, Lobrinus, Johannes Alexander, Dietrich, Pierre-Yves, Tsantoulis, Petros, Migliorini, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063622/
https://www.ncbi.nlm.nih.gov/pubmed/33898738
http://dx.doi.org/10.1212/NXG.0000000000000561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063622/
https://www.ncbi.nlm.nih.gov/pubmed/33898738
http://dx.doi.org/10.1212/NXG.0000000000000561

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