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Interactive Effects of HLA and GM Alleles on the Development of Alzheimer Disease

OBJECTIVE: We investigated whether particular immunoglobulin GM (γ marker) alleles—individually or epistatically with a known human leukocyte antigen (HLA) risk allele—were associated with the development of Alzheimer disease (AD). METHODS: Using a prospective cohort study design, we genotyped DNA s...

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Detalles Bibliográficos
Autores principales: Pandey, Janardan P., Nietert, Paul J., Kothera, Ronald T., Barnes, Lisa L., Bennett, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063623/
https://www.ncbi.nlm.nih.gov/pubmed/33898740
http://dx.doi.org/10.1212/NXG.0000000000000565