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Interactive Effects of HLA and GM Alleles on the Development of Alzheimer Disease
OBJECTIVE: We investigated whether particular immunoglobulin GM (γ marker) alleles—individually or epistatically with a known human leukocyte antigen (HLA) risk allele—were associated with the development of Alzheimer disease (AD). METHODS: Using a prospective cohort study design, we genotyped DNA s...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063623/ https://www.ncbi.nlm.nih.gov/pubmed/33898740 http://dx.doi.org/10.1212/NXG.0000000000000565 |