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Elevated Levels of miR-144-3p Induce Cholinergic Degeneration by Impairing the Maturation of NGF in Alzheimer’s Disease

Cholinergic degeneration is one of the key pathological hallmarks of Alzheimer’s disease (AD), a condition that is characterized by synaptic disorders and memory impairments. Nerve growth factor (NGF) is secreted in brain regions that receive projections from the basal forebrain cholinergic neurons....

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Detalles Bibliográficos
Autores principales: Zhou, Lan-Ting, Zhang, Juan, Tan, Lu, Huang, He-Zhou, Zhou, Yang, Liu, Zhi-Qiang, Lu, Youming, Zhu, Ling-Qiang, Yao, Chengye, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063700/
https://www.ncbi.nlm.nih.gov/pubmed/33898468
http://dx.doi.org/10.3389/fcell.2021.667412