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A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice
Disturbed neuronal activity in neuropsychiatric pathologies emerges during development and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, and synapse formation. However, how altered electrical activity early in life affects neuronal function and behavior...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063718/ https://www.ncbi.nlm.nih.gov/pubmed/33675685 http://dx.doi.org/10.1016/j.neuron.2021.02.011 |