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A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice

Disturbed neuronal activity in neuropsychiatric pathologies emerges during development and might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, and synapse formation. However, how altered electrical activity early in life affects neuronal function and behavior...

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Detalles Bibliográficos
Autores principales: Bitzenhofer, Sebastian H., Pöpplau, Jastyn A., Chini, Mattia, Marquardt, Annette, Hanganu-Opatz, Ileana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063718/
https://www.ncbi.nlm.nih.gov/pubmed/33675685
http://dx.doi.org/10.1016/j.neuron.2021.02.011