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Mechanistic analysis of actin-binding compounds that affect the kinetics of cardiac myosin–actin interaction
Actin–myosin mediated contractile forces are crucial for many cellular functions, including cell motility, cytokinesis, and muscle contraction. We determined the effects of ten actin-binding compounds on the interaction of cardiac myosin subfragment 1 (S1) with pyrene-labeled F-actin (PFA). These co...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063737/ https://www.ncbi.nlm.nih.gov/pubmed/33639160 http://dx.doi.org/10.1016/j.jbc.2021.100471 |