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Mechanistic analysis of actin-binding compounds that affect the kinetics of cardiac myosin–actin interaction

Actin–myosin mediated contractile forces are crucial for many cellular functions, including cell motility, cytokinesis, and muscle contraction. We determined the effects of ten actin-binding compounds on the interaction of cardiac myosin subfragment 1 (S1) with pyrene-labeled F-actin (PFA). These co...

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Detalles Bibliográficos
Autores principales: Roopnarine, Osha, Thomas, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063737/
https://www.ncbi.nlm.nih.gov/pubmed/33639160
http://dx.doi.org/10.1016/j.jbc.2021.100471