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RHO to the DOCK for GDP disembarking: Structural insights into the DOCK GTPase nucleotide exchange factors
The human dedicator of cytokinesis (DOCK) family consists of 11 structurally conserved proteins that serve as atypical RHO guanine nucleotide exchange factors (RHO GEFs). These regulatory proteins act as mediators in numerous cellular cascades that promote cytoskeletal remodeling, playing roles in v...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063744/ https://www.ncbi.nlm.nih.gov/pubmed/33684443 http://dx.doi.org/10.1016/j.jbc.2021.100521 |