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Mixed Pluronic—Cremophor Polymeric Micelles as Nanocarriers for Poorly Soluble Antibiotics—The Influence on the Antibacterial Activity

In this work, novel polymeric mixed micelles from Pluronic F127 and Cremophor EL were investigated as drug delivery systems for Norfloxacin as model antibiotic drug. The optimal molar ratio of surfactants was determined, in order to decrease critical micellar concentration (CMC) and prepare carriers...

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Detalles Bibliográficos
Autores principales: Tănase, Maria Antonia, Raducan, Adina, Oancea, Petruţa, Diţu, Lia Mara, Stan, Miruna, Petcu, Cristian, Scomoroşcenco, Cristina, Ninciuleanu, Claudia Mihaela, Nistor, Cristina Lavinia, Cinteza, Ludmila Otilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063824/
https://www.ncbi.nlm.nih.gov/pubmed/33804932
http://dx.doi.org/10.3390/pharmaceutics13040435