Pathogenesis and pathology of anti-neutrophil cytoplasmic antibody（ANCA）-associated vasculitis

• AAV is characterized by necrotizing small vessel vasculitis with positive serum ANCA. • MPO/PR3-ANCA and neutrophils play central roles in AAV pathogenicity. • Dysregulated complement system primes neutrophils. • MPO-ANCA directly activates neutrophils to induce NETosis followed by releasing NETs....

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Detalles Bibliográficos
Autores principales: Tsukui, Daisuke, Kimura, Yoshitaka, Kono, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Review article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063861/
https://www.ncbi.nlm.nih.gov/pubmed/33912820
http://dx.doi.org/10.1016/j.jtauto.2021.100094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063861/
https://www.ncbi.nlm.nih.gov/pubmed/33912820
http://dx.doi.org/10.1016/j.jtauto.2021.100094

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