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Regulation of translation by methylation multiplicity of 18S rRNA
SUMMARY: N(6)-methyladenosine (m(6)A) is a conserved ribonucleoside modification that regulates many facets of RNA metabolism. Using quantitative mass spectrometry, we find that the universally conserved tandem adenosines at the 3′ end of 18S rRNA, thought to be constitutively di-methylated (m(6)(2)...
Autores principales: | Liu, Kuanqing, Santos, Daniel A., Hussmann, Jeffrey A., Wang, Yun, Sutter, Benjamin M., Weissman, Jonathan S., Tu, Benjamin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8063911/ https://www.ncbi.nlm.nih.gov/pubmed/33691096 http://dx.doi.org/10.1016/j.celrep.2021.108825 |
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