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A protocol for in vivo analysis of liver tumorigenesis in mice using sleeping beauty transposon system

Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer death worldwide. However, the pathogenesis of HCC is complicated, and the drugs used for HCC treatment are limited. The following protocol combines a genetically engineered mouse model (GEMM) with a sleeping beauty system to establ...

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Detalles Bibliográficos
Autores principales: He, Lingli, Yu, Wentao, Lu, Yi, Zhang, Wenxiang, Xu, Jinjin, Zhang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064019/
https://www.ncbi.nlm.nih.gov/pubmed/33912846
http://dx.doi.org/10.1016/j.xpro.2021.100445