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Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma

Epithelial-mesenchymal transition (EMT) is an evolutionarily conserved developmental program that has been implicated in tumorigenesis and confers metastatic properties upon cancer cells. ZEB1 is a master transcription factor that activates the EMT process in various cancers. ZEB1 is reportedly degr...

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Detalles Bibliográficos
Autores principales: Dong, Xiao, Han, Yang, Zhang, Encheng, Wang, Yuqi, Zhang, Pingzhao, Wang, Chenji, Zhong, Lin, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064142/
https://www.ncbi.nlm.nih.gov/pubmed/33833131
http://dx.doi.org/10.18632/aging.202823