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Tumor suppressor DCAF15 inhibits epithelial-mesenchymal transition by targeting ZEB1 for proteasomal degradation in hepatocellular carcinoma
Epithelial-mesenchymal transition (EMT) is an evolutionarily conserved developmental program that has been implicated in tumorigenesis and confers metastatic properties upon cancer cells. ZEB1 is a master transcription factor that activates the EMT process in various cancers. ZEB1 is reportedly degr...
Autores principales: | Dong, Xiao, Han, Yang, Zhang, Encheng, Wang, Yuqi, Zhang, Pingzhao, Wang, Chenji, Zhong, Lin, Li, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064142/ https://www.ncbi.nlm.nih.gov/pubmed/33833131 http://dx.doi.org/10.18632/aging.202823 |
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