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BMP5 silencing inhibits chondrocyte senescence and apoptosis as well as osteoarthritis progression in mice

In this study, we using the in vivo destabilization of the medial meniscus (DMM) mouse model to investigate the role of bone morphogenetic protein 5 (BMP5) in osteoarthritis (OA) progression mediated via chondrocyte senescence and apoptosis. BMP5 expression was significantly higher in knee articular...

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Detalles Bibliográficos
Autores principales: Shao, Yan, Zhao, Chang, Pan, Jianying, Zeng, Chun, Zhang, Hongbo, Liu, Liangliang, Fan, Kai, Liu, Xin, Luo, Bingsheng, Fang, Hang, Bai, Xiaochun, Zhang, Haiyan, Cai, Daozhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064147/
https://www.ncbi.nlm.nih.gov/pubmed/33744859
http://dx.doi.org/10.18632/aging.202708