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Nuclear envelope tethering inhibits the formation of ALT-associated PML bodies in ALT cells

Telomere length homeostasis is essential for maintaining genomic stability and cancer proliferation. Telomerase-negative cancer cells undergo recombination-mediated alternative lengthening of telomeres. Telomeres associate with the nuclear envelope through the shelterin RAP1 and nuclear envelope SUN...

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Detalles Bibliográficos
Autores principales: Yang, Chia-Wei, Hsieh, Meng-Hsun, Sun, Hao-Jhe, Teng, Shu-Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064153/
https://www.ncbi.nlm.nih.gov/pubmed/33820871
http://dx.doi.org/10.18632/aging.202810