Cargando…

Regulation of PINX1 expression ameliorates lipopolysaccharide-induced lung injury and alleviates cell senescence during the convalescent phase through affecting the telomerase activity

PIN2/TERF1-interacting telomerase inhibitor 1 (PINX1) is necessary for telomerase reverse transcriptase (TERT) elements to bind at telomeres and non-telomere sites. We aimed to investigate the role of PINX1 and TERT in lipopolysaccharide (LPS)-induced lung injury during acute stage and convalescent...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Shujing, Jiang, Bin, Yu, Haiyang, Song, Dongqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064186/
https://www.ncbi.nlm.nih.gov/pubmed/33819185
http://dx.doi.org/10.18632/aging.202779