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ASIC1 and ASIC3 mediate cellular senescence of human nucleus pulposus mesenchymal stem cells during intervertebral disc degeneration

Stem cell approaches have become an attractive therapeutic option for intervertebral disc degeneration (IVDD). Nucleus pulposus mesenchymal stem cells (NP-MSCs) participate in the regeneration and homeostasis of the intervertebral disc (IVD), but the molecular mechanisms governing these processes re...

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Detalles Bibliográficos
Autores principales: Ding, Jingyu, Zhang, Renjie, Li, Huimin, Ji, Qiang, Cheng, Xiaomin, Thorne, Rick Francis, Hondermarck, Hubert, Liu, Xiaoying, Shen, Cailiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064223/
https://www.ncbi.nlm.nih.gov/pubmed/33824228
http://dx.doi.org/10.18632/aging.202850