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Exosomal miR-222 from adriamycin-resistant MCF-7 breast cancer cells promote macrophages M2 polarization via PTEN/Akt to induce tumor progression

Exosome-mediated intercellular communication is considered to be an effective mode for malignant cells to transform biological behaviors in stromal cells. However, the mechanisms by which exosomes modulate macrophages within tumor microenvironment remain largely unclear. In this study, we found that...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Xian, Wang, Dan-Dan, Zhu, Bei, Zhu, Yi-Zhi, Zheng, Lin, Feng, Zhen-Qing, Qin, Xi-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064228/
https://www.ncbi.nlm.nih.gov/pubmed/33752173
http://dx.doi.org/10.18632/aging.202802