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Regulation of TGFβ Signalling by TRPV4 in Chondrocytes

The growth factor TGFβ and the mechanosensitive calcium-permeable cation channel TRPV4 are both important for the development and maintenance of many tissues. Although TRPV4 and TGFβ both affect core cellular functions, how their signals are integrated is unknown. Here we show that pharmacological a...

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Detalles Bibliográficos
Autores principales: Woods, Steven, Humphreys, Paul A., Bates, Nicola, Richardson, Sophie Alice, Kuba, Shweta Yogesh, Brooks, Imogen R., Cain, Stuart A., Kimber, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064313/
https://www.ncbi.nlm.nih.gov/pubmed/33805168
http://dx.doi.org/10.3390/cells10040726