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Model of the RNA Polymerase Complex of the SARS-CoV-2 Virus with Favipiravir

A model of a multidomain complex is constructed using molecular modeling methods to explain the mechanism of the inhibitory effect of favipiravir on RNA-dependent RNA polymerase (RdRp) of the SARS-CoV-2 coronavirus. As the initial atomic coordinates, we use cryoelectron microscopy data for the apo f...

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Detalles Bibliográficos
Autores principales: Polyakov, I. V., Grigorenko, B. L., Nemukhin, A. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064419/
http://dx.doi.org/10.1134/S1990793121010255