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Model of the RNA Polymerase Complex of the SARS-CoV-2 Virus with Favipiravir

A model of a multidomain complex is constructed using molecular modeling methods to explain the mechanism of the inhibitory effect of favipiravir on RNA-dependent RNA polymerase (RdRp) of the SARS-CoV-2 coronavirus. As the initial atomic coordinates, we use cryoelectron microscopy data for the apo f...

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Detalles Bibliográficos
Autores principales:	Polyakov, I. V., Grigorenko, B. L., Nemukhin, A. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pleiades Publishing 2021
Materias:	Chemical Physics of Biological Processes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064419/ http://dx.doi.org/10.1134/S1990793121010255

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