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Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation

AIMS: Prior studies have focused on the role of the kidney and vasculature in salt-induced modulation of blood pressure; however, recent data indicate that sodium accumulates in tissues and can activate immune cells. We sought to examine mechanisms by which salt causes activation of human monocytes...

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Detalles Bibliográficos
Autores principales: Ruggeri Barbaro, Natalia, Van Beusecum, Justin, Xiao, Liang, do Carmo, Luciana, Pitzer, Ashley, Loperena, Roxana, Foss, Jason D, Elijovich, Fernando, Laffer, Cheryl L, Montaniel, Kim R, Galindo, Cristi L, Chen, Wei, Ao, Mingfang, Mernaugh, Raymond L, Alsouqi, Aseel, Ikizler, Talat A, Fogo, Agnes B, Moreno, Heitor, Zhao, Shilin, Davies, Sean S, Harrison, David G, Kirabo, Annet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064439/
https://www.ncbi.nlm.nih.gov/pubmed/33038226
http://dx.doi.org/10.1093/cvr/cvaa207