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Design and Synthesis of Novel Symmetric Fluorene-2,7-Diamine Derivatives as Potent Hepatitis C Virus Inhibitors

Hepatitis C virus (HCV) is an international challenge. Since the discovery of NS5A direct-acting antivirals, researchers turned their attention to pursue novel NS5A inhibitors with optimized design and structure. Herein we explore highly potent hepatitis C virus (HCV) NS5A inhibitors; the novel anal...

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Detalles Bibliográficos
Autores principales: Mousa, Mai H. A., Ahmed, Nermin S., Schwedtmann, Kai, Frakolaki, Efseveia, Vassilaki, Niki, Zoidis, Grigoris, Weigand, Jan J., Abadi, Ashraf H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064491/
https://www.ncbi.nlm.nih.gov/pubmed/33806139
http://dx.doi.org/10.3390/ph14040292