Mdm2-Mediated Downmodulation of GRK2 Restricts Centrosome Separation for Proper Chromosome Congression

The timing of centrosome separation and the distance moved apart influence the formation of the bipolar spindle, affecting chromosome stability. Epidermal growth factor receptor (EGFR) signaling induces early centrosome separation through downstream G protein-coupled receptor kinase GRK2, which phos...

Descripción completa

Detalles Bibliográficos
Autores principales: Reglero, Clara, Ortiz del Castillo, Belén, Rivas, Verónica, Mayor, Federico, Penela, Petronila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064503/
https://www.ncbi.nlm.nih.gov/pubmed/33806062
http://dx.doi.org/10.3390/cells10040729

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064503/
https://www.ncbi.nlm.nih.gov/pubmed/33806062
http://dx.doi.org/10.3390/cells10040729

Ejemplares similares