Priming of myelin-specific T cells in the absence of dendritic cells results in accelerated development of Experimental Autoimmune Encephalomyelitis

Experimental autoimmune encephalomyelitis (EAE) is an established animal model of multiple sclerosis (MS). Inflammatory CD4(+) T cell responses directed against CNS antigens, including myelin proteolipid protein (PLP), are key mediators of EAE. Dendritic cells (DCs) are critical for the induction of...

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Detalles Bibliográficos
Autores principales: Luu, Thaiphi, Cheung, Julie F., Baccon, Jennifer, Waldner, Hanspeter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064509/
https://www.ncbi.nlm.nih.gov/pubmed/33891644
http://dx.doi.org/10.1371/journal.pone.0250340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064509/
https://www.ncbi.nlm.nih.gov/pubmed/33891644
http://dx.doi.org/10.1371/journal.pone.0250340

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