Cargando…
Priming of myelin-specific T cells in the absence of dendritic cells results in accelerated development of Experimental Autoimmune Encephalomyelitis
Experimental autoimmune encephalomyelitis (EAE) is an established animal model of multiple sclerosis (MS). Inflammatory CD4(+) T cell responses directed against CNS antigens, including myelin proteolipid protein (PLP), are key mediators of EAE. Dendritic cells (DCs) are critical for the induction of...
Autores principales: | Luu, Thaiphi, Cheung, Julie F., Baccon, Jennifer, Waldner, Hanspeter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064509/ https://www.ncbi.nlm.nih.gov/pubmed/33891644 http://dx.doi.org/10.1371/journal.pone.0250340 |
Ejemplares similares
-
Myelin morphology and axon pathology in demyelination during experimental autoimmune encephalomyelitis
por: Bando, Yoshio
Publicado: (2015) -
Targeting Non-classical Myelin Epitopes to Treat Experimental Autoimmune Encephalomyelitis
por: Wang, Xiaohua, et al.
Publicado: (2016) -
Tolerogenic dendritic cells in experimental autoimmune encephalomyelitis, specific tolerance induction?
por: Sellés-Moreno, Carla, et al.
Publicado: (2012) -
Damage to the Optic Chiasm in Myelin Oligodendrocyte Glycoprotein–Experimental Autoimmune Encephalomyelitis Mice
por: Herrera, Sheryl L, et al.
Publicado: (2014) -
Inhibition of experimental autoimmune encephalomyelitis by tolerance-promoting DNA vaccination focused to dendritic cells
por: Castor, Timo, et al.
Publicado: (2018)