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Mesencephalic astrocyte-derived neurotrophic factor is secreted from interferon-γ–activated tumor cells through ER calcium depletion

The most successful immunotherapeutic agents are blocking antibodies to either programmed cell death-1 (PD-1), an inhibitory receptor expressed on T lymphocytes, or to its ligand, programmed cell death-ligand 1 (PD-L1). Nevertheless, many patients do not respond, and additional approaches, specifica...

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Detalles Bibliográficos
Autores principales: Peled, Michael, Bar-Lev, Tali H., Talalai, Efrosiniia, Aspitz, Haggar Zoë, Daniel-Meshulam, Inbal, Bar, Jair, Kamer, Iris, Ofek, Efrat, Mor, Adam, Onn, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064521/
https://www.ncbi.nlm.nih.gov/pubmed/33891607
http://dx.doi.org/10.1371/journal.pone.0250178