Avoiding organelle mutational meltdown across eukaryotes with or without a germline bottleneck

Mitochondrial DNA (mtDNA) and plastid DNA (ptDNA) encode vital bioenergetic apparatus, and mutations in these organelle DNA (oDNA) molecules can be devastating. In the germline of several animals, a genetic “bottleneck” increases cell-to-cell variance in mtDNA heteroplasmy, allowing purifying select...

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Detalles Bibliográficos
Autores principales: Edwards, David M., Røyrvik, Ellen C., Chustecki, Joanna M., Giannakis, Konstantinos, Glastad, Robert C., Radzvilavicius, Arunas L., Johnston, Iain G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064548/
https://www.ncbi.nlm.nih.gov/pubmed/33891583
http://dx.doi.org/10.1371/journal.pbio.3001153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064548/
https://www.ncbi.nlm.nih.gov/pubmed/33891583
http://dx.doi.org/10.1371/journal.pbio.3001153

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