Reduced Expression of Hippocampal GluN2A-NMDAR Increases Seizure Susceptibility and Causes Deficits in Contextual Memory

N-methyl-D-aspartate receptors are heterotetramers composed of two GluN1 obligatory subunits and two regulatory subunits. In cognitive-related brain structures, GluN2A and GluN2B are the most abundant regulatory subunits, and their expression is subjected to tight regulation. During development, Glu...

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Detalles Bibliográficos
Autores principales: Acutain, Maria Florencia, Griebler Luft, Jordana, Vazquez, Cecila Alejandra, Popik, Bruno, Cercato, Magalí C., Epstein, Alberto, Salvetti, Anna, Jerusalinsky, Diana A., de Oliveira Alvares, Lucas, Baez, Maria Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064689/
https://www.ncbi.nlm.nih.gov/pubmed/33897358
http://dx.doi.org/10.3389/fnins.2021.644100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064689/
https://www.ncbi.nlm.nih.gov/pubmed/33897358
http://dx.doi.org/10.3389/fnins.2021.644100

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